What medications cause tendon damage?
Drug-induced tendinopathy, including tendinitis and tendon rupture, is most frequently associated with aromatase inhibitors, fluoroquinolones, glucocorticoids, and statins.
Can antibiotics cause tendon problems?
ANTIBIOTICS THAT CAN CAUSE TENDON DAMAGE
The class of antibiotics known as fluoroquinolones have been found to create an increased risk of tendon damage. In May of 2016, the FDA issued its strongest warning yet for anyone using these antibiotics.
Which antibiotic can cause tendonitis as its side effect?
Taking levofloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward.
Why do antibiotics weaken tendons?
In short, fluoroquinolones interfere with your collagen turnover in your tendons. All the cells in our bodies, including our collagen fibres in our tendons, are constantly renewing – old ones are being absorbed and replaced by new healthy ones. These antibiotics seem to stop the body from forming new collagen fibres.
What can weaken tendons?
With repetitive or prolonged activities, forceful exertion, awkward and static postures, vibration, and localized mechanical stress, the tendons fibers can tear apart in much the same way a rope becomes frayed.
How do I know if my tendon is torn?
An injury that is associated with the following signs or symptoms may be a tendon rupture:
- A snap or pop you hear or feel.
- Severe pain.
- Rapid or immediate bruising.
- Marked weakness.
- Inability to use the affected arm or leg.
- Inability to move the area involved.
- Inability to bear weight.
- Deformity of the area.
What diseases cause tendon problems?
Tendinitis is a condition where the connective tissues between your muscles and bones (tendons) become inflamed. Often caused by repetitive activities, tendinitis can be painful.
These diseases can include:
- Rheumatoid arthritis.
- Blood or kidney diseases.
How common is tendonitis with ciprofloxacin?
Data about the incidence of quinolone-associated Achilles tendon rupture is scarce. In a study with prescription event monitoring, the incidence of tendon rupture was estimated as 2.7 per 10 000 patients for ofloxacin and 0.9 per 10 000 patients for ciprofloxacin.
What is the most common antibiotic for a UTI?
Drugs commonly recommended for simple UTIs include:
- Trimethoprim/sulfamethoxazole (Bactrim, Septra, others)
- Fosfomycin (Monurol)
- Nitrofurantoin (Macrodantin, Macrobid)
- Cephalexin (Keflex)
What are the most common side effects of ciprofloxacin?
The most common side effects of ciprofloxacin tablets and liquid are feeling sick (nausea) and diarrhoea. Avoid taking the tablets or liquid together with dairy products like milk, cheese and yoghurt.
Do statins affect tendons?
Statins have adverse effects on the tendon. Many studies have analyzed the relationship between atorvastatin and skeletal muscles. Atorvastatin administered after the surgical repair of a ruptured tendon appears to affect revascularization, collagenization, inflammatory cell infiltration, and collagen construction.