Is methotrexate the best treatment for rheumatoid arthritis?

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Is methotrexate worth the risk?

Methotrexate is one of the most effective and widely used medications for treating inflammatory types of arthritis. It’s also one of the safest arthritis drugs, despite a common misconception among many patients that methotrexate is highly toxic.

Which is better for rheumatoid arthritis methotrexate or hydroxychloroquine?

Otrexup (methotrexate) is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Plaquenil (hydroxychloroquine) has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis.

How long do RA patients stay on methotrexate?

Many patients with rheumatoid arthritis have stayed on this drug for 20 years or more.

Do you gain weight on methotrexate?

Official Answer. Methotrexate was shown to cause a modest amount of weight gain over 6 months, in a study measuring weight changes in people with rheumatoid arthritis. The patients who were most likely to gain weight when starting methotrexate, were patients who had recently lost weight due to rheumatoid arthritis.

How long do you stay on methotrexate?

Methotrexate can stay in your body for some time, so you need to stop taking methotrexate at least 6 months before trying for a baby. If you become pregnant while taking methotrexate, do not stop taking your medicine and speak to your doctor as soon as possible.

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Does methotrexate work better than hydroxychloroquine?

Safety variables at 6 month were within normal physiological ranges and did not differ in groups (p>0.05) indicating that both methotrexate and hydroxychloroquine were effective and safe to use in rheumatoid arthritis. The difference in the incidence of adverse effects, total or individual, was almost nil.

Can I take vitamin D with methotrexate?

No interactions were found between methotrexate and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can you ever get off methotrexate?

Myth: You can stop taking methotrexate once you feel better

You may feel much better than you did before you started methotrexate: less pain, swelling, morning stiffness or fatigue. If you feel better but still have low disease activity, the ACR’s treatment guidelines recommend against stopping or lowering your dose.

What drugs should not be taken with methotrexate?

Some specific NSAIDs that should be avoided while taking methotrexate include:

  • Aspirin (Zorprin, Excedrin)
  • Bromfenac (Prolensa, Bromday)
  • Etodolac (Lodine)
  • Fenoprofen (Nalfon)
  • Ibuprofen (Advil, Motrin)
  • Naproxen (Aleve, Naprosyn)
  • Magnesium salicylate (Doan’s)
  • Salsalate.